Featured Bibliography

Evaluation of a new CT/NG/TV/MG Real-Time PCR Kit (Vircell) versus the Allplex STI Essential Assay (Seegene) for the diagnosis of sexually transmitted infections

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This study evaluated CT/NG/TV/MG Real-Time PCR Kit Vircell for the detection of four major sexually transmitted infection pathogens across different anatomical sample types. The assay showed high diagnostic performance compared with Allplex STI Essential Assay, with 99.53% overall sensitivity, 99.84% specificity and excellent concordance. These results support its use as a reliable molecular option for routine STI diagnosis in clinical laboratories.

Comparative performance of the Platelia Aspergillus Antigen and Aspergillus galactomannan antigen VirClia Monotest immunoassays in serum and lower respiratory tract specimens: a “real-life” experience

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Comparison of two automated commercial assays for routine detection of anti-hepatitis E Virus IgM antibodies in clinical samples

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Retrospective Multicenter Evaluation of the VirClia Galactomannan Antigen Assay for the Diagnosis of Pulmonary Aspergillosis with Bronchoalveolar Lavage Fluid Samples from Patients with Hematological Disease

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Comparison of the performance of two galactomannan detection tests: Platelia Aspergillus Ag and Aspergillus galactomannan Ag VirClia Monotest

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Evaluation of a combined detection of SARS-CoV-2 and its variants using real-time allele-specific PCR strategy: An advantage for clinical practice

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Evaluation of a novel clia monotest assay for the detection of anti-hepatitis e virus-igg and igm: A retrospective comparison with a line blot and an elisa

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Comprehensive, comparative evaluation of 25 automated SARS-CoV-2 serology assays

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Detection of intrathecal IgG antibody for varicella and measles diagnosis by evaluation and comparison of a commercial IgG chemiluminescent immunoassay with two ELISAs

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VirClia® Measles and Varicella-Zoster IgG monotests was evaluated for determining antibody index in paired CSF and serum samples. The automated CLIA assays showed strong agreement with established ELISA methods and high diagnostic performance for both measles and VZV IgG. These findings highlight the potential of VirClia® technology to support laboratory investigation of infectious neurological disorders.

Comparative evaluation of chemiluminescent immunoassay and enzyme‑linked immunosorbent assays for the diagnosis of West Nile virus infections

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West Nile virus diagnosis relies mainly on serological detection, particularly when the viremic phase has passed. In this comparative study, WNV VIRCLIA® IgM and IgG monotests showed strong agreement with established ELISA methods and high diagnostic performance in serum samples. The automated monotest format offers a practical CLIA-based solution to support West Nile virus diagnosis in routine laboratory workflows.

Bibliography

Li Y, Min L, Zhang X. Usefulness of procalcitonin (PCT), C-reactive protein (CRP), and white blood cell (WBC) levels in the differential diagnosis of acute bacterial, viral, and mycoplasmal respiratory tract infections in children. BMC Pulmonary Medicine. 2021 Dec 1;21(1).
Lier C, Gouarin S, Ollivier I, Ferey J, Schanen C, Dina J, et al. Evaluation de la performance des tests sérologiques semi-automatisés VirClia® pour la détection des IgM et des IgG anti-virus de l’hépatite E (VHE). CHU Caen, France; 2019. Report.
Linares-Palomino J, Gutiérrez J, López-Espada C, Ros E, Moreno J, Pérez T, et al. Chlamydia pneumoniae y enfermedad cerebrovascular [Chlamydia pneumoniae and cerebrovascular disease]. Rev Neurol. 2001;32(3):201-6
Lindroth Y, Hansson L, Forslund O. An automated commercial open access assay for detection of Mycoplasma genitalium macrolide resistance. APMIS. 2025 Jan;133(1):e13477.
Lindsley MD. Serological Diagnosis of Fungal Infections. In: Manual of Molecular and Clinical Laboratory Immunology. Wiley; 2024. p. 489–520.
Liu J, Ai H, Xiong Y, Li F, Wen Z, Liu W, et al. Prevalence and correlation of infectious agents in hospitalized children with acute respiratory tract infections in central China. PLoS ONE. 2015 Mar 9;10(3).
Liu L, Lei X, Xiao X, Yang J, Li J, Ji M, et al. Epidemiological and Clinical Characteristics of Patients With Coronavirus Disease-2019 in Shiyan City, China. Frontiers in Cellular and Infection Microbiology. 2020 May 22;10.
Liu Q, Chen MX, Cai YC, Li YY, Wang ZY, Guo YH, et al. Trypanosoma dionisii in China: ecology and tentative epidemiology. Infectious Diseases of Poverty. 2025 Dec 1;14(1).
lo Cascio G, Lepera V, Sorrentino A, Caleca D, Gigante P, Tocci G, et al. Evaluation of a New Automated Mono-Test for the Detection of Aspergillus Galactomannan: Comparison of Aspergillus Galactomannan Ag VirCLIA® Mono-Test with PlateliaTM Aspergillus Ag ELISA Assay. Journal of Fungi. 2024 Nov 1;10(11).
Lo Cascio G, Naso L, Sorrentino A, Maccacaro L, Cover E, Bombieri E, et al. Value of beta-D-glucan and CAGTA biomarkers in diagnosing invasive candidiasis among medical and surgical patients. In: ECCMID; 2018; Madrid, Spain. Abstract.
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